Darier’s Disease, a rare genetic skin disorder affecting one in 30,000 individuals, has long been a challenge for medical experts. Characterized by persistent, itchy, and crusted skin lesions, Darier’s Disease can be both physically and emotionally taxing for those who live with it. But recent advances in gene therapy offer a promising new approach to treating this often-debilitating condition. In this article, we’ll explore the groundbreaking research and what it means for those affected by Darier’s Disease.
The Genetics Behind Darier’s Disease
Darier’s Disease is an autosomal dominant genetic disorder caused by a mutation in the ATP2A2 gene, which encodes the SERCA2 protein.